A FACILE METHOD FOR CONTROLLING THE REACTION EQUILIBRIUM OF SPHINGOLIPID CERAMIDE N-DEACYLASE FOR LYSO-GLYCOSPHINGOLIPID PRODUCTION[S]

A facile method for controlling the reaction equilibrium of sphingolipid ceramide N-deacylase for lyso-glycosphingolipid production[S]

Lyso-glycosphingolipids (lyso-GSLs), the N-deacylated forms of glycosphingolipids (GSLs), are important synthetic intermediates for the preparation of GSL analogs.Although lyso-GSLs can be produced by hydrolyzing natural GSLs using sphingolipid ceramide N-deacylase (SCDase), the yield for this reaction is usually low because SCDase also catalyzes t

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